Dissemination

Dissemination will be achieved through the following activities:

- Set up or updating of European guidelines for diagnosis of OSAS, evaluation of cardiovascular risk in OSAS patients, and medico-legal implications of daytime somnolence to be published in the international literature together with related joint studies generated within the network;

- Diffusion of basic information on OSAS and its cardiovascular consequences by a section of the website dedicated to patients and their relatives and by documents summarizing the results of the Action targeted at the medical community, the patient community and the public opinion;

- COST meetings will be planned in conjunction with European or other National/International Medical Conferences (for example, organized by the European Respiratory Society, the European Sleep Society, or the European Society of Cardiology). This strategy will increase the visibility of the Action at a multidisciplinary level;

- Elaboration and diffusion (web site) of a directory of European laboratories, groups and individual researchers working on OSAS and cardiovascular risk for purposes of diagnostic activity? or basic research;

- Set up a list of reference labs working on mechanisms of cardiovascular complications in OSAS. Investigators of the identified labs will be in charge of spreading information on recent key findings, relevant publications, diagnostic applications through organization of specific workshops;

- Publication on the web site of annual reports.


Publications of the B26 COST Action jointly published by COST Members or resulting form the activity of the Network:

Eur Respir Monograph: Respiratory Disease in the Elderly (in press, 2009): Bonsignore MR, McNicholas WT. Sleep-disordered breathing in the elderly.

Eur Respir J Series (in press, 2009): The genetic and cardiovascular aspects of the obstructive sleep apnoea/hypopnoea syndrome

R.L. Riha, T. Gislasson and K. Diefenbach. The phenotype and genotype of adult obstructive sleep apnoea/hypopnoea syndrome

J.F. Garvey, C.T. Taylor and W.T. McNicholas. Cardiovascular disease in OSAS: the role of intermittent hypoxia and inflammation.


- Riha RL, McNicholas WT.
The genetic and cardiovascular aspects of obstructive sleep apnoea/hypopnoea
syndrome.
Eur Respir J. 2009 Feb;33(2):233-6.

- Bonsignore, Maria Rosaria and Anna Zito. 2008. Metabolic effects of
the obstructive sleep apnea syndrome and cardiovascular risk. Archives
Of Physiology And Biochemistry. 114(4):255-260. 

- Ryan S, McNicholas WT.
Intermittent hypoxia and activation of inflammatory molecular pathways in OSAS.
Arch Physiol Biochem. 2008 Oct;114(4):261-6. Review.


- Trayhurn, Paul, Bohan Wang and I. Stuart Wood. 2008. 
Hypoxia and the endocrine and signalling role of white
adipose tissue. Archives Of Physiology And Biochemistry.
114(4):267-276.

- Vgontzas, Alexandros N., Edward O. Bixler,
George P. Chrousos and Slobodanka Pejovic. 2008. Obesity and sleep
disturbances: Meaningful sub-typing of obesity. Archives Of Physiology
And Biochemistry. 114(4):224-236. 

4 Eckardt, Kristin, Henrike Sell and Juergen
Eckel. 2008. Novel aspects of adipocyte-induced skeletal muscle insulin
resistance. Archives Of Physiology And Biochemistry. 114(4):287-298.
< http://www.informaworld.com/10.1080/13813450802404761 >.
(accessed 11 February 2009).

- Perrini, Sebastio, Anna Leonardini, Luigi Laviola and Francesco Giorgino. 2008. 
Biological specificity of visceral adipose tissue and therapeutic intervention.
Archives Of Physiology And Biochemistry. 114(4):277-286.

- Körner, Antje, Jürgen Kratzsch, Ruth Gausche, Susann Blüher, Thomas Kapellen, 
Ferdinand Pulzer, Mirja Behrens and Wieland Kiess. 2008. 
Metabolic syndrome in children and adolescents – risk for sleep-disordered
breathing and obstructive sleep-apnoea syndrome?. 
Archives Of Physiology And Biochemistry. 114(4):237-243.

- Lavie, Lena, Larissa Dyugovskaya and Andrey Polyakov. 2008. 
Biology of peripheral blood cells in obstructive sleep
apnea – the tip of the iceberg. Archives Of Physiology And
Biochemistry. 114(4):244-254.

- Vgontzas, Alexandros N.. 2008. Does obesity
play a major role in the pathogenesis of sleep apnoea and its
associated manifestations via inflammation, visceral adiposity, and
insulin resistance?. Archives Of Physiology And Biochemistry.
114(4):211-223.
- Rodenstein D; Cost-B26 Action on Sleep Apnoea Syndrome.
Driving in Europe: the need of a common policy for drivers with obstructive sleep
apnoea syndrome. J Sleep Res. 2008 Sep;17(3):281-4. Epub 2008 Jul 22.

- Riha RL, Diefenbach K, Jennum P, McNicholas WT; Management Committee, COST B26
Action on Sleep Apnoea Syndrome.
Genetic aspects of hypertension and metabolic disease in the obstructive sleep
apnoea-hypopnoea syndrome. Sleep Med Rev. 2008 Feb;12(1):49-63. Review.

- Alonderis A, Barbé F, Bonsignore M, Calverley P, De Backer W, Diefenbach K,
Donic V, Fanfulla F, Fietze I, Franklin K, Grote L, Hedner J, Jennum P, Krieger
J, Levy P, McNicholas W, Montserrat J, Parati G, Pascu M, Penzel T, Riha R,
Rodenstein D, Sanna A, Schulz R, Sforza E, Sliwinski P, Tomori Z, Tonnesen P,
Varoneckas G, Zielinski J, Kostelidou K; COST Action B-26.
Medico-legal implications of sleep apnoea syndrome: driving license regulations
in Europe. Sleep Med. 2008 May;9(4):362-75.

- Parati G, Lombardi C, Narkiewicz K.
 Sleep apnea: epidemiology, pathophysiology, and relation to cardiovascular risk. 
Am J Physiol Regul Integr Comp Physiol. 2007 Oct;293(4):R1671-83. Review.

- McNicholas WT.
Cardiovascular outcomes of CPAP therapy in obstructive sleep apnea syndrome.
Am J Physiol Regul Integr Comp Physiol. 2007 Oct;293(4):R1666-70. Review.
 

- McNicholas WT, Bonsignore MR; Management Committee of EU COST ACTION B26.
 Sleep apnoea as an independent risk factor for cardiovascular disease: current
evidence, basic mechanisms and research priorities.
Eur Respir J. 2007 Jan;29(1):156-78. Review.